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Search Results for " AD 1 "

阻害剤

天然化合物

1746

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T39678	Multitarget AD inhibitor-1
	Multitarget AD inhibitor-1 is a reversible and selective inhibitor of butyrylcholinesterase (BuChE) with IC50 values of 7.22 μM and 1.55 μM for human BuChE (hBuChE) and equine serum BuChE (eqBuChE), respectively. Additio...
T60150	(1S,2R)-Alicapistat		Cysteine Protease
	(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, with promising implications for Alzheimer's disease (AD) therapy [1]. This compound ef...		Cysteine Protease
T77042	Aducanumab	BIIB037	Beta Amyloid
	Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease...		Beta Amyloid
T4364	Aftin-4	Aftin 4,Aftin4	Beta Amyloid , Gamma-secretase
	Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus...		Beta Amyloid , Gamma-secretase
T11175	Elenbecestat	E2609	Beta-Secretase , BACE
	Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.		Beta-Secretase , BACE
TP1930L1	Spexin acetate(1370290-58-6 free base)		Neuropeptide Y Receptor
	Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits...		Neuropeptide Y Receptor
T14178	Alicapistat	ABT-957	Others
	Alicapistat (ABT-957) is a human calpains 1 and 2 inhibitor. It can potentially be used to treat Alzheimer's disease (AD).		Others
T32330	JWB1-84-1 3HCl	JWB1 84 1 3HCl,JWB1 84 1 trihydrochloride,JWB1-84-1 trihydrochloride,JWB1841 trihydrochloride
	JWB1-84-1 3HCl, as a neuroprotective agent, can act by improving cognitive performances in a transgenic mouse model of AD.
T76738	Bapineuzumab
	Bapineuzumab, an anti-β-amyloid protein (APP) monoclonal antibody, is utilized in Alzheimer’s disease (AD) research [1].
T80878	Vanutide cridificar	PF 05236806,ACC-001
	Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].
T78807	YIAD-0205
	YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familial AD mutations [1].
T76816	Lokivetmab
	Lokivetmab, an Anti-Canine IL31 Recombinant Antibody, is a monoclonal antibody targeting canine IL-31, utilized in research related to atopic dermatitis (AD) in dogs [1].
T76926	Bepranemab
	Bepranemab (UCB 0107), a humanized full-length IgG4 monoclonal antibody, targets the central tau epitope (amino acids 235-250) and is utilized in Alzheimer’s disease (AD) research [1].
T78333	Rocatinlimab	AMG 451,KHK4083
	Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated IgG1 anti-OX40 monoclonal antibody indicated for atopic dermatitis (AD) research [1].
T79752	DDC 2′,3′-O-disulfate
	DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].
T79010	Lp-PLA2-IN-12		Phospholipase
	Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), and cardiovascular conditions...		Phospholipase
T35892	Q134R	Q134R
	Q134R, a neuroprotective derivative of hydroxyquinoline, effectively inhibits nuclear factor of activated T-cell (NFAT) signaling and possesses the ability to cross the blood-brain barrier. This compound shows promise fo...
T80700	β Amyloid(17-28) human
	β-Amyloid(17-28) human is a fragment of the β-amyloid peptide (Abeta) associated with Alzheimer's disease (AD), promoting the aggregation of the full-length β-Amyloid40 into toxic aggregates [1]. This lipid-induced amylo...
T79011	TrkB-IN-1		Trk receptor
	TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties. It has been shown to reverse cognitive deficits in an Alzheimer's disease (AD) mouse model, thus serving ...		Trk receptor
T62578	BuChE-IN-1
	BuChE-IN-1 (Compound 23) is a potent, highly blood-brain barrier-permeable, low cytotoxicity inhibitor of butyrylcholinesterase (BuChE). BuChE-IN-1 is a BuChE inhibitor that has the potential to be used in the study of A...
T64181	SEH/AChE-IN-1
	sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 has a cumulative effect against neuroinflammation and memory impairment. sEH/AChE-IN-1 ha...
T61408	BChE-IN-2
	BChE-IN-2 (compound 22) is a highly effective inhibitor of BChE, exhibiting a Ki value of 0.099 μM. This compound represents a promising pyrimidine and pyridine derivative for investigating Alzheimer's disease (AD). [1]
T77028	Gosuranemab
	Gosuranemab (BMS-986168), a humanized IgG4 anti-tau monoclonal antibody, specifically targets human N-terminal tau residues 15-22. It holds potential for Alzheimer’s disease (AD) research [1] [2].
T75930	β-Amyloid (1-43)(human) TFA
	β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42. Additionally, this compound demonstrates associations with both sAPPα and ...
T64214	NXPZ-2
	NXPZ-2 is an orally active Keap1-Nrf2protein-protein interaction (PPI) inhibitor (Ki: 95 nM, EC50: 120 and 170 nM). NXPZ-2 dose-dependently attenuates Aβ[1-42]-induced cognitive disturbances, enhances neuronal number and...
T62719	AChE/BACE1/GSK3β-IN-1
	AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β. AChE/BACE1/GSK3β-IN-1 can be used to study Alzheimer's disease (AD).
T76395	(Met(O)35)-Amyloid β-Protein (1-42)
	(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of Aβ40. This compound is utilized in Alzheimer’s disease (AD) re...
T60739	Y13g
	Y13g is the potent inhibitor of Interleukin-6 (IL-6) and acetylcholinesterase(AChE) which are two important targets implicated in Alzheimer's Disease(AD) progression. Y13g reverses the memory deficit induced by STZ as we...
TP1228	β-Amyloid (1-16)	Amyloid β-Protein (1-16),β-Amyloid 1-16
	β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is...
T78874	GSK-3β inhibitor 15
	GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-induced iNOS expression. It demonstrates neuroprotective propert...
T76372	TRAF6 peptide
	TRAF6 peptide, a specific TRAF6-p62 inhibitor, effectively inhibits NGF-dependent TrkA ubiquitination, showcasing strong research potential for neurological conditions including Alzheimer's disease (AD), Parkinson's, ALS...
T79684	5-HT6R antagonist 1		5-HT Receptor
	Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability but also reverses MK-801-induced memory impairments in rats, ...		5-HT Receptor
T79548	AChE/BChE-IN-13
	AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal inhibitory concentrations (IC50) of 20.89 μM for AChE and 17.3...
T79533	PDE5-IN-10
	PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM, enhanced in vitro microsomal stability (t 1/2 = 44.6 min), and ex...
T78221	TRAF6 peptide TFA		E1/E2/E3 Enzyme
	TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA. This peptide demonstrates promising research applications in various neurological disorde...		E1/E2/E3 Enzyme
T61388	HAChE/Aβ1-42-IN-1
	Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and excellent brain-blood barrier (BBB) penetration with a broad sa...
T80118	α-Synuclein (61-95) (human)
	α-Synuclein (61-95) (human) constitutes the hydrophobic core of α-synuclein and is implicated in inducing neuronal cell death. This segment is utilized in the study of neurodegenerative conditions such as Alzheimer's dis...
T61785	BChE-IN-6
	BChE-IN-6 (compound 12) is a highly effective inhibitor of BChE, showcasing a Ki value of 0.182 μM. Notably, BChE-IN-6 exhibits significant chelating abilities towards Zn 2+. Due to these characteristics, BChE-IN-6 serve...
T61342	BChE-IN-13
	BChE-IN-13 (Compound 17c) is an orally active, potent, and selective inhibitor of Butyrylcholinesterase (BChE). It exhibits IC50 values of 0.22 μM and 0.016 μM for eqBChE and hBChE, respectively. BChE-IN-13 demonstrates ...
T74818	JNK3 inhibitor-8
	JNK3 Inhibitor-8 is a potent, selective, and orally active inhibitor that can cross the blood-brain barrier, targeting JNK3 with IC50 values of 21 nM for JNK3, 2203 nM for JNK2, and >10000 nM for JNK1. This compound demo...
T38002	LEO 39652
	LEO 39652, a dual-soft PDE4 inhibitor, demonstrates potent inhibition of PDE4 subtypes A, B, C, and D with respective IC50 values of 1.2 nM, 1.2 nM, 3.0 nM, and 3.8 nM. Additionally, it inhibits TNF-α with an IC50 of 6.0...
T75730	[D-Arg25]-Neuropeptide Y (human)
	[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY), a Y1 receptor selective agonist, plays a role in Alzheimer's disease (AD) and safeguards rat cortical neurons from β-Amyloid toxicity [1].
T61087	THK-5105
	THK-5105, an arylquinoline derivative, demonstrates a high binding affinity for tau fibrils, protein aggregates, and tau-rich Alzheimer's disease (AD) brain homogenates, indicative of its potential as a tau imaging PET (...
T76394	Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42)
	Amyloid β-Protein (36-42), the 36-42 fragment of β-Amyloid, consists of a polypeptide chain of 36-43 amino acids and is a primary constituent of amyloid plaques in Alzheimer's disease (AD) patients' brains. β-Amyloid oli...
T78596	CAD031
	CAD031, a more active derivative of the Alzheimer's disease (AD) targeting agent J147, exhibits neuroprotective and memory-enhancing properties. It has been shown to enhance memory, improve dendritic structure, and stimu...
T82242	HAChE-IN-6
	hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM. It also demonstrates inhibitory effects on human butyrylcholinesterase (hBuChE) and glycogen synthase kin...
T37148	TML-6
	TML-6, an oral curcumin derivative, demonstrates inhibitory effects on the synthesis of β-amyloid precursor protein and β-amyloid (Aβ). Additionally, TML-6 exhibits upregulation of Apo E, suppression of NF-κB and mTOR, a...
T74817	JNK3 inhibitor-7
	JNK3 inhibitor-7, a potent and orally active compound that can cross the blood-brain barrier, acts as a JNK3 inhibitor with IC50 values of 53 nM for JNK3, 973 nM for JNK2, and 1039 nM for JNK1. Demonstrating significant ...
T60907	THK-5117
	THK-5117 is an arylquinoline derivative with the potential as a PET probe for tau imaging. THK-5117 shows high binding affinity to tau fibrils with a Ki value of 10.5 nM. THK-5117 also shows high binding affinity to tau ...
T76221	Leptin (116-130)
	Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell ...

Compounds

Multitarget AD inhibitor-1

Target: Cysteine Protease

Synonym: Aftin 4,Aftin4

Target: Beta Amyloid, Gamma-secretase

Elenbecestat

T11175

Synonym: E2609

Target: Beta-Secretase, BACE

Spexin acetate(1370290-58-6 free base)

TP1930L1

Synonym:

Target: Neuropeptide Y Receptor

Synonym: JWB1 84 1 3HCl,JWB1 84 1 trihydrochloride,JWB1-84-1 trihydrochloride,JWB1841 trihydrochloride

Synonym: PF 05236806,ACC-001

Synonym: AMG 451,KHK4083

Target:

DDC 2′,3′-O-disulfate

Target: Phospholipase

β Amyloid(17-28) human

β-Amyloid (1-43)(human) TFA

AChE/BACE1/GSK3β-IN-1

T62719

Synonym:

Target:

(Met(O)35)-Amyloid β-Protein (1-42)

Synonym: Amyloid β-Protein (1-16),β-Amyloid 1-16

Target: 5-HT Receptor

Target: E1/E2/E3 Enzyme

α-Synuclein (61-95) (human)

[D-Arg25]-Neuropeptide Y (human)

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42)

カタログ番号	製品名	別名	ターゲット
T6S0721	Orientin	Lutexin,Luteolin-8-glucoside	Others
	1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...		Others
TN3218	7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one		Beta Amyloid , PI3K , mTOR
	7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's dise...		Beta Amyloid , PI3K , mTOR
T75544	AChE/BChE-IN-11
	AChE/BChE-IN-11 (compound 1), a natural product derived from artichoke leaves, is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 70 μM for AChE and 71 μM for BChE, re...
T75512	Bleformin A
	Bleformin A, a natural product isolated from Bletilla striata, serves as a potent butyrylcholinesterase (BChE) inhibitor, exhibiting an IC50 value of 5.2 μM. It is utilized in Alzheimer's disease (AD) research [1].
T75514	Blestrin D
	Blestrin D, a potent mixed-type butyrylcholinesterase (BChE) inhibitor with an IC50 value of 8.1 μM, is isolated from Bletilla striata and has applications in Alzheimer's disease (AD) research [1].
T75511	BChE-IN-10
	BChE-IN-10 (compound 6), isolated from Bletilla striata, is a potent mixed-type butyrylcholinesterase (BChE) inhibitor exhibiting an IC50 value of 6.4 μM. It is utilized in Alzheimer's disease (AD) research [1].
T75513	BChE-IN-12
	BChE-IN-12, also known as compound 12, is a potent non-competitive inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 2.3 μM. Derived from Bletilla striata, it is utilised in research related to Alzheimer's ...
T75628	Methyl ganoderate A acetonide
	Methyl ganoderate A acetonide, a lanostane triterpene derived from the fruiting bodies of Ganoderma lucidum, serves as a potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 18.35 μM. Its efficacy in inhibi...

天然物製品

Orientin

T6S0721

Synonym: Lutexin,Luteolin-8-glucoside

Target: Others

7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one

TN3218

Synonym:

Target: Beta Amyloid, PI3K, mTOR

Methyl ganoderate A acetonide

T75628

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04770	RIOK1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions ...
TMPY-01284	METTL11A Protein, Human, Recombinant (GST)	Human	E. coli
	METTL11A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 52.2 kDa and the accession number is A0A024R8E4.
TMPY-01285	METTL11A Protein, Human, Recombinant	Human	E. coli
	METTL11A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.5 kDa and the accession number is A0A024R8E4.
TMPY-01479	SPG3A Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin...
TMPJ-00023	SNCA Protein, Human, Recombinant (His)	Human	E. coli
	SNCA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P37840.
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPY-02221	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1.
TMPY-03884	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)	Human	E. coli
	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067...
TMPY-03885	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)	Human	E. coli
	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067...
TMPK-00763	Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPH-02996	KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)	Mycolicibacterium smegmatis	E. coli
	Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,...
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and...
TMPY-03653	CTRL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is...
TMPY-02393	Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, high...
TMPY-00519	Gastrokine 1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in...
TMPY-02300	BIN1 Protein, Human, Recombinant (His)	Human	E. coli
	Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-02112	FGFR4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPY-02335	OSMR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	OSMR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 83.7 kDa and the accession number is O70458-1.
TMPY-00322	DEC-205 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant...
TMPY-02115	R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)	Human	HEK293 Cells
	R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel...
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-04261	CD64 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD64 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is P12314-1.
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-00464	M-CSF/CSF1 Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	M-CSF/CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1.
TMPY-02412	ENO1 Protein, Human, Recombinant (His)	Human	E. coli
	ENO1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P06733-1.
TMPY-01920	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-00735	Cathepsin S Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin S Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is P25774-1.
TMPY-06074	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPY-01725	Leptin Receptor Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Leptin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is P48357-1.
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-00414	LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
TMPY-01082	Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His)	RSV	HEK293 Cells
	Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession num...
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-02154	FAP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1.
TMPY-00756	FGF-1 Protein, Human, Recombinant	Human	E. coli
	FGF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P05230-1.
TMPY-05201	Siglec-2/CD22 Protein, Human, Recombinant	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1.
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1.
TMPY-01139	PDGFRA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is P10747-1.
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S)	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-02312	CSF3R/G-CSFR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CSF3R/G-CSFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q99062-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His)	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
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RIOK1 Protein, Human, Recombinant (His & GST)

TMPY-04770

Species: Human

Expression System: Baculovirus Insect Cells

METTL11A Protein, Human, Recombinant (GST)

TMPY-01284

Species: Human

Expression System: E. coli

METTL11A Protein, Human, Recombinant

TMPY-01285

Species: Human

Expression System: E. coli

SPG3A Protein, Human, Recombinant (GST)

TMPY-01479

Species: Human

Expression System: Baculovirus Insect Cells

SNCA Protein, Human, Recombinant (His)

TMPJ-00023

Species: Human

Expression System: E. coli

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

TMPY-00668

Species: Human

Expression System: HEK293 Cells

Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)

TMPY-02110

Species: Human

Expression System: E. coli

Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)

TMPY-02221

Species: Human

Expression System: E. coli

Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)

TMPY-03884

Species: Human

Expression System: E. coli

Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)

TMPY-03885

Species: Human

Expression System: E. coli

Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00763

Species: Human

Expression System: HEK293 Cells

KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)

TMPH-02996

Species: Mycolicibacterium smegmatis

Expression System: E. coli

Serpin A3 Protein, Human, Recombinant (His)

TMPY-01303

Species: Human

Expression System: HEK293 Cells

Amyloid Precursor Protein, Human, Recombinant (hFc)

TMPJ-00782

Species: Human

Expression System: HEK293 Cells

CTRL Protein, Human, Recombinant (His)

TMPY-03653

Species: Human

Expression System: HEK293 Cells

Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His)

TMPY-02393

Species: Mouse

Expression System: Baculovirus Insect Cells

Gastrokine 1 Protein, Human, Recombinant (His)

TMPY-00519

Species: Human

Expression System: Baculovirus Insect Cells

BIN1 Protein, Human, Recombinant (His)

TMPY-02300

Species: Human

Expression System: E. coli

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

TMPY-02501

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

TMPY-03745

Species: Human

Expression System: HEK293 Cells

FGFR4 Protein, Human, Recombinant (His)

TMPY-02112

Species: Human

Expression System: HEK293 Cells

OSMR Protein, Mouse, Recombinant (His)

TMPY-02335

Species: Mouse

Expression System: HEK293 Cells

DEC-205 Protein, Human, Recombinant (His)

TMPY-00322

Species: Human

Expression System: HEK293 Cells

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

TMPY-02115

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

TMPY-04529

Species: Human

Expression System: Baculovirus Insect Cells

CD64 Protein, Human, Recombinant (His)

TMPY-04261

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

TMPY-01147

Species: Human

Expression System: HEK293 Cells

M-CSF/CSF1 Protein, Mouse, Recombinant

TMPY-00464

Species: Mouse

Expression System: HEK293 Cells

ENO1 Protein, Human, Recombinant (His)

TMPY-02412

Species: Human

Expression System: E. coli

BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)

TMPY-01920

Species: Human

Expression System: HEK293 Cells

Cathepsin S Protein, Human, Recombinant (His)

TMPY-00735

Species: Human

Expression System: HEK293 Cells

B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06074

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

Leptin Receptor Protein, Human, Recombinant (His)

TMPY-01725

Species: Human

Expression System: HEK293 Cells

Fas Ligand Protein, Human, Recombinant (His)

TMPY-03956

Species: Human

Expression System: P. pastoris (Yeast)

LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)

TMPY-00414

Species: Human

Expression System: HEK293 Cells

Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His)

TMPY-01082

Species: RSV

Expression System: HEK293 Cells

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

TMPY-06076

Species: Human

Expression System: HEK293 Cells

BTN3A3 Protein, Human, Recombinant (His)

TMPY-03967

Species: Human

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (His)

TMPY-02154

Species: Human

Expression System: HEK293 Cells

FGF-1 Protein, Human, Recombinant

TMPY-00756

Species: Human

Expression System: E. coli

Siglec-2/CD22 Protein, Human, Recombinant

TMPY-05201

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (mFc)

TMPY-05827

Species: Human

Expression System: HEK293 Cells

PDGFRA Protein, Human, Recombinant (His)

TMPY-01139

Species: Human

Expression System: HEK293 Cells

CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-05354

Species: Human

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant (C103S)

TMPY-00820

Species: Human

Expression System: HEK293 Cells

CSF3R/G-CSFR Protein, Human, Recombinant (His)

TMPY-02312

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130S, His)

TMPY-05220

Species: Human

Expression System: HEK293 Cells

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カタログ番号	製品名
L9840	Anti-Alzheimer's Disease Compound Library		986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

ライブラリー

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986